Researchers describe nanoparticles behavior in vivo

Nanoparticles are actively employed in medicine as contrast agents as well as for diagnosis and therapy of various diseases. However, the development of novel multifunctional nanoagents is impeded by the difficulty of monitoring their blood circulation. Researches from the Moscow Institute of Physics and Technology, the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of RAS, Moscow Engineering Physics Institute, Prokhorov General Physics Institute of RAS, and Sirius University have developed a new noninvasive method of nanoparticle measurement in the bloodstream that boasts a high time resolution. This technique has revealed the basic parameters that affect particle lifetime in the bloodstream, which may potentially lead to discovery of new, more effective nanoagents to be used in biomedicine. The results of the study have been published in the Journal of Controlled Release. Continue reading at Physorg